Rabbit anti-TWIST1 Recombinant Monoclonal Antibody [BLR156J]
Catalog #
TWIST1
Human
ICC
,IP
,WB
Rabbit
Recombinant Monoclonal
BLR156J
Whole IgG
between 1 and 50
IgG
Unconjugated
Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Phosphate Buffered Saline (PBS) containing 0.2% BSA and 0.09% Sodium Azide
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Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
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TWIST1 is a basic helix-loop-helix (bHLH) transcription factor that plays an important role in embryonic development. TWIST1 forms both homodimers and heterodimers that bind to DNA E box sequences and regulate the transcription of genes involved in cranial suture closure during skull development. TWIST1 may also regulate neural tube closure, limb development and brown fat metabolism. The TWIST1 gene is hypermethylated and overexpressed in multiple human cancers, and the encoded protein promotes tumor cell invasion and metastasis, as well as metastatic recurrence. [taken from NCBI Entrez Gene (Gene ID: 7291)].
Alternate Names
ACS3; B-HLH DNA binding protein; bHLHa38; BPES2; BPES3; class A basic helix-loop-helix protein 38; CRS; CRS1; CSO; H-twist; SCS; SWCOS; TWIST; twist basic helix-loop-helix transcription factor 1; twist homolog 1; TWIST homolog of drosophila; twist-related protein 1
Applications