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Rabbit anti-GITR/TNFRSF18 Recombinant Monoclonal Antibody [BLR068G]

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

GITR/TNFRSF18

Reactivity:

Human

Platforms:

PhenoImager™ HT

Host:

Rabbit

Clonality:

Recombinant Monoclonal

Clone:

BLR068G

Format:

Whole IgG

Immunogen:

between 191 and 241 (C-term)

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Purified

100 µl (50+ tests)

10 µl (5+ tests)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free


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Additional Product Information

GITR/TNFRSF18 is a member of the TNF-receptor superfamily. It has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by regulatory T cells. GITR/TNFRSF18 also plays a role in the regulation of CD3-driven T-cell activation and programmed cell death. [provided by RefSeq, Feb 2011] [taken from NCBI Entrez Gene (Gene ID: 8784)].

8784

TNFRSF18

TNF receptor superfamily member 18

Q9Y5U5

Tumor necrosis factor receptor superfamily member 18

Alternate Names

activation-inducible TNFR family receptor; AITR; CD antigen CD357; CD357; GITR; GITR-D; glucocorticoid-induced TNFR-related protein; TNF receptor superfamily activation-inducible protein; tumor necrosis factor receptor superfamily member 18

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.