Mouse anti-PCNA Monoclonal Antibody, Purified [PC10]
Catalog #
PCNA
Human
,Mouse
Flow Cyt
,ICC
,IHC
,IP
,WB
COMET™
Mouse
Monoclonal
PC10
Whole IgG
recombinant rat PCNA
IgG2a
Unconjugated
Purified
Product Details
Mouse,
Human
Human
2 - 8 °C
1 year from date of receipt
Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide
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Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide, BSA-Free
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PCNA (Proliferating Cell Nuclear Antigen) was first identified as a factor expressed in the nuclei of replicating cells. PCNA plays a role in both DNA synthesis and repair. PCNA functions as a processivity factor for DNA polymerase by acting as a DNA clamp that tethers the polymerase catalytic units to the DNA template. The structure of PCNA is that of a trimeric ring that encircles and slides along replicating DNA. PCNA interacts with and is regulated by several proteins involved in cell cycle control and check point processes.
Alternate Names
ATLD2; cyclin; DNA polymerase delta auxiliary protein; PCNA; proliferating cell nuclear antigen
Applications