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Mouse anti-CD74 Monoclonal Antibody, Purified [LN2]

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

CD74

Reactivity:

Human

Host:

Mouse

Clonality:

Monoclonal

Clone:

LN2

Format:

Whole IgG

Immunogen:

human SU-DHL-4 lymphoma cells

Isotype:

IgG1

Conjugate:

Unconjugated

Purity:

Purified

100 µl (50+ tests)

10 µl (5+ tests)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide


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Additional Product Information

CD74 plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. CD74 also serves as cell surface receptor for the cytokine MIF. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P04233].

972

CD74

CD74 molecule

P04233

HLA class II histocompatibility antigen gamma chain

Alternate Names

CD antigen CD74; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule, major histocompatibility complex, class II invariant chain; DHLAG; gamma chain of class II antigens; HLA class II histocompatibility antigen gamma chain; HLADG; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; Ia antigen-associated invariant chain; Ia-associated invariant chain; Ia-GAMMA; II; MHC HLA-DR gamma chain; p33

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots are performed using Goat anti-Mouse IgG Heavy and Light Chain Antibody (Cat. No. A90-216P).