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Primary Antibodies  

Rabbit anti-HD-PTP Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

HD-PTP

Reactivity:

Human

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 1586 and 1636

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Mouse,

Rat

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

His domain-containing protein tyrosine phosphatase (HD-PTP) plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. HD-PTP may act as a negative regulator of Ras-mediated mitogenic activity.This protein plays a role in ciliogenesis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H3S7].

25930

PTPN23

protein tyrosine phosphatase, non-receptor type 23

Q9H3S7

Tyrosine-protein phosphatase non-receptor type 23

Alternate Names

HDPTP; HD-PTP; his domain-containing protein tyrosine phosphatase; protein tyrosine phosphatase TD14; PTP-TD14; tyrosine-protein phosphatase non-receptor type 23

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.