Rabbit anti-CDK8 Antibody
Catalog #
CDK8
Human
IP
Rabbit
Polyclonal
Whole IgG
between 370 and 420
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
X_laevis,
X_tropicalis
Human
2 - 8 °C
1 year from date of receipt
Cyclin-dependent kinase 8 (CDK8) associates with cyclin C and is a component of the RNA polymerase II holoenzyme complex which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. CDK8 has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery [taken from NCBI Entrez Gene (GeneID: 1024)].
Alternate Names
CDK8 protein kinase; cell division protein kinase 8; cyclin-dependent kinase 8; K35; mediator complex subunit CDK8; mediator of RNA polymerase II transcription subunit CDK8; protein kinase K35
Applications