Rabbit anti-PCNA Antibody
Catalog #
PCNA
Human
,Mouse
Flow Cyt
,IHC
,IP
,WB
PhenoImager™ HT
Rabbit
Polyclonal
Whole IgG
between 75 and 125
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human,
Mouse
Chicken,
Bovine,
Rat
Human
2 - 8 °C
1 year from date of receipt
PCNA (Proliferating Cell Nuclear Antigen) was first identified as a factor expressed in the nuclei of replicating cells. PCNA plays a role in both DNA synthesis and repair. PCNA functions as a processivity factor for DNA polymerase by acting as a DNA clamp that tethers the polymerase catalytic units to the DNA template. The structure of PCNA is that of a trimeric ring that encircles and slides along replicating DNA. PCNA interacts with and is regulated by several proteins involved in cell cycle control and check point processes.
Alternate Names
ATLD2; cyclin; DNA polymerase delta auxiliary protein; PCNA; proliferating cell nuclear antigen
Applications