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Ushering in the Second Wave of Checkpoint Blockade Therapies

Ki-67: A Nuclear Antigen Uniquely Qualified as a Marker of Cellular Proliferation

Contributed by Jane Naberhuis, Ph.D.


Ki-67 is a well characterized proliferation-associated nuclear antigen with great utility in histopathology. It can be used to identify proliferating cells in healthy tissues, but is most often used as a diagnostic tool in various cancers ranging from breast to thyroid.