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E-cadherin: Keeping Cells Together

E-cadherin: Keeping Cells Together

Contributed by Aliyah Weinstein, Ph.D.

 

Cell-cell adhesion is critical for cells and organisms to function, as it is the mechanism that keeps tissues and organs intact. The proteins that form cell-cell junctions, members of the cadherin family, are also important for transmitting extracellular signals into the cell. Cadherins form part of a type of cell-cell junction known as the adherens junction.

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