vPARP Antibody

PARP4 [poly(ADP-ribose) polymerase family, member 4] catalyzes the formation of ADP-ribose polymers covalently attached to proteins using NAD+ as a substrate. There are 6 mammalian PARP enzymes: PARP1, PARP2, PARP3, PARP4/vPARP, PARP5/Tankyrase-1, and PARP6/Tankyrase-2. PARP4 is also known as vault PARP (vPARP) due to its association with the vault particle, a 13MDa cytoplasmic ribonucleoprotein complex whose barrel-shaped structure resembles arched cathedral ceilings. vPARP has also been identified separate from the vault particle. It has been localized to the nuclear pore, mitotic spindle, and cytoplasm. It also has been shown to associate with telomerase activity. Studies of vPARP knockout mice show an increased susceptibility to carcinogen-induced tumorigenesis.
PARP4
poly(ADP-ribose) polymerase family member 4
Poly [ADP-ribose] polymerase 4
:  193 kDa vault protein ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 1 ADP-ribosyltransferase diphtheria toxin-like 4 ADPRTL1 ARTD4 H5 proline-rich I-alpha-I-related p193 PARP-4 PARPL PARP-related PARP-related/IalphaI-related H5/proline-rich PH5P poly (ADP-ribose) polymerase family, member 4 poly(ADP-ribose) synthetase poly(ADP-ribosyl)transferase-like 1 vault poly(ADP-ribose) polymerase vault protein, 193-kDa VAULT3 von Willebrand factor A domain containing 5C VPARP VWA5C More... Less...
Product
Specifications
Ordering Information
Human
IP
Between 1400 and 1450
$339
$99
Human
WB, IP, IHC-P
Between 1674 to 1724
$339
$229
$99
Human
WB, IP, IHC-P
Includes: 1 each of A301-953A and A301-954A
$472
Includes: 1 each of A301-953A and A301-954A
Human
IHC-P
Between 1674 and 1724
$360
$99