p16INK4a Antibody

p16INK4a is a negative regulator of CDK4 and CDK6 kinase activity and cell cycle progression. p16INK4a regulates the cell cycle by inhibiting cyclin/CDK complex formation and the phosphorylation of the retinoblastoma protein (pRb). The gene which encodes p16INK4a, CDKN2A, is frequently mutated or deleted in a wide variety of tumors and is known to be an important tumor suppressor gene. The CDKN2A gene also generates a distinct transcript variant and protein, p14ARF, from an alternate open reading frame (ARF).
cyclin dependent kinase inhibitor 2A
Cyclin-dependent kinase inhibitor 2A
:  alternative reading frame ARF CDK4 inhibitor p16-INK4 CDK4I CDKN2 cell cycle negative regulator beta CMM2 cyclin-dependent kinase 4 inhibitor A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) INK4 INK4a MLM MTS1 MTS-1 multiple tumor suppressor 1 p14 p14ARF p16 p16-INK4 p16INK4a p19 p19Arf TP16 More... Less...
Ordering Information
Between 106 and 156