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p16INK4a Antibody

p16INK4a is a negative regulator of CDK4 and CDK6 kinase activity and cell cycle progression. p16INK4a regulates the cell cycle by inhibiting cyclin/CDK complex formation and the phosphorylation of the retinoblastoma protein (pRb). The gene which encodes p16INK4a, CDKN2A, is frequently mutated or deleted in a wide variety of tumors and is known to be an important tumor suppressor gene. The CDKN2A gene also generates a distinct transcript variant and protein, p14ARF, from an alternate open reading frame (ARF).
cyclin dependent kinase inhibitor 2A
Cyclin-dependent kinase inhibitor 2A
:  alternative reading frame ARF CDK4 inhibitor p16-INK4 CDK4I CDKN2 cell cycle negative regulator beta CMM2 cyclin-dependent kinase 4 inhibitor A cyclin-dependent kinase inhibitor 2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) INK4 INK4A MLM MTS1 MTS-1 multiple tumor suppressor 1 P14 P14ARF P16 P16INK4 p16-INK4 P16INK4A P16-INK4A P19 P19ARF TP16 More... Less...
Ordering Information
between 106 and 156