UVRAG Antibody

UV radiation resistance associated gene (UVRAG) was first identified as a gene that could complement UV sensitivity in xeroderma pigmentosum cells. UVRAG may have tumor suppressor activity as mutations in the UVRAG gene have been associated with various human colon cancer cells and tissues. UVRAG has been shown to interact with Beclin 1 (Bcl-2-interacting protein), a protein that forms a complex with class III PI-3-kinase (PI3KC3) and is involved in autophagy. In this complex, UVRAG is proposed to function as a positive regulator of autophagy and a negative regulator of the growth of tumor cells.
UVRAG
UV radiation resistance associated
UV radiation resistance-associated gene protein
:  beclin 1 binding protein DHTX disrupted in heterotaxy p63 UV radiation resistance associated gene VPS38
Product
Specifications
Ordering Information
Human
WB, IP
Between 575 and 625
$339
$229
$99
Human
WB, IP, IHC
Between 649 and 699
$339
$229
$99
Human
WB, IP, IHC
Includes: 1 each of A301-995A and A301-996A
$472
Includes: 1 each of A301-995A and A301-996A
Human, Mouse
IHC
Between 649 and 699
$360
$99