Transcription elongation is one step in the multistage process of transcription that involves the polymerization of nucleoside monophosphates into a ribonucleotide transcript catalyzed by the multisubunit complex RNA Pol II. Transcriptional regulation involves positive factors that promote sufficient elongation rates and processivity as well as negative elongation factors that repress transcription elongation. SUPT6H is hypothesized to play a role in enhancing the rate of transcription elongation in association with RNA Pol II by mobilizing histones and modulating chromatin structure.
histone chaperone suppressor of Ty6•
suppressor of Ty (S.cerevisiae) 6 homolog•
suppressor of Ty 6 homolog•
suppressor of Ty 6 homolog (S. cerevisiae)•
tat-cotransactivator 2 protein•