Due to inclement weather, Bethyl will be closed Tuesday, January 16 and re-open Wednesday, January 17th at noon. Orders will not be processed until Bethyl re-opens. This is a developing weather situation and may continue to change. Thank you!
Raf kinase inhibitor protein (RKIP) binds ATP, opioids and phosphatidylethanolamine. RKIP has lower affinity for phosphatidylinositol and phosphatidylcholine. it is a serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). RKIP inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P30086].