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Pc2 Antibody

Pc2 (polycomb 2 homolog) is also known as CBX4. Pc2 is an E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. It is a component of the Polycomb group (PcG) multiprotein complex, PRC1 (polycomb repressive complex), a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. The PcG-PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility [taken from the Universal Protein Resource (UniProt)].
chromobox 4
E3 SUMO-protein ligase CBX4
:  chromobox homolog 4 (Pc class homolog, Drosophila) chromobox protein homolog 4 chromobox-like protein 4 E3 SUMO-protein ligase CBX4 hPc2 NBP16 NS5ATP1-binding protein 16 Pc class 2 homolog PC2 polycomb 2 homolog
Ordering Information
Human, Mouse
between 150 and 200
Human, Mouse
Between 150 and 200