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PTRH2/BIT1 Antibody

Peptidyl-tRNA hydrolase 2 (PTRH2) is a mitochondrial protein with two putative domains, an N-terminal mitochondrial localization sequence, and a UPF0099 domain. In vitro assays suggest that this protein possesses peptidyl-tRNA hydrolase activity, to release the peptidyl moiety from tRNA, thereby preventing the accumulation of dissociated peptidyl-tRNA that could reduce the efficiency of translation. This protein also plays a role regulating cell survival and death. It promotes survival as part of an integrin-signaling pathway for cells attached to the extracellular matrix (ECM), but also promotes apoptosis in cells that have lost their attachment to the ECM, a process called anoikos [taken from NCBI Entrez Gene (Gene ID: 51651)].
peptidyl-tRNA hydrolase 2
Peptidyl-tRNA hydrolase 2, mitochondrial
:  bcl-2 inhibitor of transcription 1 BIT1 CFAP37 CGI-147 cilia and flagella associated protein 37 IMNEPD peptidyl-tRNA hydrolase 2, mitochondrial PTH PTH 2 PTH2
Ordering Information
Between 129 and 179