PHD2 Antibody

PHD2 is one of 4 PHD (PHD1-4) enzymes that function as oxygen sensors and are responsible for the post-translational modification of HIF-1alpha, a component of a transcriptional complex involved in oxygen homeostasis. During normoxic levels, PHDs catalyze the hydroxylation of prolyl residues on HIF-1alpha and target it for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. The PHD isoforms appear to function in a non-redundant manner and may differ in their expression patterns and their catalytic selectivity.
egl-9 family hypoxia inducible factor 1
Egl nine homolog 1
:  C1orf12 ECYT3 EGL nine (C.elegans) homolog 1 egl nine homolog 1 (C. elegans) egl nine-like protein 1 egl-9 family hypoxia-inducible factor 1 HALAH HIF prolyl hydroxylase 2 HIFPH2 HIF-PH2 HIF-prolyl hydroxylase 2 HPH2 HPH-2 hypoxia-inducible factor prolyl hydroxylase 2 PHD2 prolyl hydroxylase domain-containing protein 2 SM20 SM-20 zinc finger MYND domain-containing protein 6 ZMYND6 More... Less...
Ordering Information
Between 1 and 50