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PHD1 Antibody

PHD1 is one of 4 PHD (PHD1-4) enzymes that function as oxygen sensors and are responsible for the post-translational modification of HIF-1alpha, a component of a transcriptional complex involved in oxygen homeostasis. During normoxic levels, PHDs catalyze the hydroxylation of prolyl residues on HIF-1alpha and target it for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. The PHD isoforms appear to function in a non-redundant manner and may differ in their expression patterns and their catalytic selectivity.
egl-9 family hypoxia inducible factor 2
Egl nine homolog 2
:  egl nine homolog 2 EIT6 EIT-6 estrogen-induced tag 6 HIFPH1 HIF-PH1 HIF-prolyl hydroxylase 1 HPH-1 HPH-3 hypoxia-inducible factor prolyl hydroxylase 1 PHD1 prolyl hydroxylase domain-containing protein 1
Ordering Information
Between 1 and 50