Bethyl will be closed on Thursday, July 4 and Friday, July 5 in observation of the 4th of July holiday. We will re-open Monday, July 8.

PD-L1 Antibody

PD-L1 is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. PD-L1 is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma [taken from NCBI Entrez Gene (Gene ID: 55193)].
CD274 molecule
Programmed cell death 1 ligand 1
:  B7 homolog 1 B7-H B7H1 B7-H1 CD antigen CD274 CD274 antigen PDCD1 ligand 1 PDCD1L1 PDCD1LG1 PDL1 PD-L1 programmed cell death 1 ligand 1 Programmed death ligand 1
Ordering Information
between 250 to 290 (C-term)