NIR Antibody

Novel INHAT repressor (NIR) acts as an inhibitor of histone acetyltransferase activity; it prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. NIR acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. It is involved in the regulation of p53/TP53-dependent apoptosis and it associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter [taken from the Universal Protein Resource (UniProt)].
NOC2 like nucleolar associated transcriptional repressor
Nucleolar complex protein 2 homolog
:  NET15 NET7 NIR NOC2L nucleolar associated transcriptional repressor NOC2-like protein novel INHAT (inhibitor of histone acetyltransferase) repressor novel INHAT repressor nucleolar complex associated 2 homolog nucleolar complex protein 2 homolog PPP1R112 protein NOC2 homolog protein phosphatase 1, regulatory subunit 12 More... Less...
Ordering Information
Between 699 and 749