MGRN1 Antibody

MGRN1 (mahogunin RING finger protein 1) is an E3 ubiquitin-protein ligase that mediates monoubiquitination at multiple sites of TSG101 in the presence of UBE2D1, but not of UBE2G1, nor UBE2H. MGRN1 plays a role in the regulation of endosome-to-lysosome trafficking. It impairs MC1R- and MC4R-signaling by competing with GNAS-binding to MCRs and inhibiting agonist-induced cAMP production but does not promote MC1R ubiquitination [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O60291].
MGRN1
mahogunin ring finger 1
E3 ubiquitin-protein ligase MGRN1
:  KIAA0544 mahogunin ring finger 1, E3 ubiquitin protein ligase mahogunin RING finger protein 1 mahogunin, ring finger 1 probable E3 ubiquitin-protein ligase MGRN1 RING finger protein 156 RNF156
Product
Specifications
Ordering Information
Human
WB, IP
Between 400 and 450
$339
$229
$99
Human
IP
Between 505 and 555
$339
$99
Human
WB, IP
Includes: 1 each of A302-912A and A302-913A
$472
Includes: 1 each of A302-912A and A302-913A