INT11 has been identified as a component of the twelve-subunit integrator complex that functions in RNA Pol II mediated 3’-end mRNA processing of the U1 and U2 small nuclear RNAs (snRNAs). INT11 is a beta-lactamase family member that has sequence similarity to the cleavage and polyadenylation specificity factors CPSF-73 and CPSF-100.
cleavage and polyadenylation-specific factor 3-like protein•
integrator complex subunit 11•
protein related to CPSF subunits of 68 kDa•
related to CPSF subunits 68 kDa•