GRB10 Antibody

Growth factor receptor-bound protein 10 (GRB10) is a member of a family of adaptor proteins that bind to a variety of growth factor receptors to regulate receptor signaling and mediate signals for a variety of processes such as metabolism, growth, apoptosis, and migration. As a dimer, via its BPS (between PH and SH2) and SH2 (src-homology 2) domains, GRB10 associates with the insulin receptor (IR) as well as the insulin-like growth factor receptor (IGFR). GRB10’s association with the IR has been shown to have inhibitory effects on insulin-induced kinase signaling; however studies have also reported that GRB10 can also have positive effects on IR signaling. It is suggested that GRB10 can serve in cellular functions independent of an interaction with the IR.
GRB10
growth factor receptor bound protein 10
Growth factor receptor-bound protein 10
:  Grb-10 GRB10 adapter protein GRB10 adaptor protein GRB-IR insulin receptor-binding protein Grb-IR IRBP maternally expressed gene 1 MEG1 RSS
Product
Specifications
Ordering Information
Human
WB, IP
Between 1 and 50
$339
$229
$99
Human
IP, IHC
Between 100 and 150
$339
$99
Human
WB, IP, IHC
Includes: 1 each of A301-734A and A301-735A
$472
Includes: 1 each of A301-734A and A301-735A
Human
IHC
Between 100 and 150
$360
$99