Due to inclement weather, Bethyl will be closed Tuesday, January 16 and re-open Wednesday, January 17th at noon. Orders will not be processed until Bethyl re-opens. This is a developing weather situation and may continue to change. Thank you!
Glucose-6-phosphate isomerase (GPI) is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. GPI functions in different capacities inside and outside the cell. In the cytoplasm, GPI is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in the GPI gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment [taken from NCBI Entrez Gene (Gene ID: 2821)].