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FLASH Antibody

Caspase-8-binding protein FLICE-associated huge protein (FLASH) is a component of the death-inducing signaling complex (DISC) that mediates CD95-induced apoptosis and caspase-8 activation. FLASH has also been identified as a component of Cajal bodies (CBs) and promyelocytic (PML) nuclear bodies. It is proposed that translocation of FLASH from nuclear bodies to caspase-rich regions of the mitochondria in response to CD95 activation provides a link between CD95 signaling, the nucleus, and the apoptotic pathway.
CASP8AP2
caspase 8 associated protein 2
CASP8-associated protein 2
:  CASP8-associated protein 2 CED-4 FLASH FLASH homolog RIP25 FLICE associated huge FLICE-associated huge protein human FLASH RIP25
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