FIH-1 Antibody

Factor inhibiting HIF-1 (FIH-1) hydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). FIH-1 functions as an oxygen sensor, and under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. FIH-1 is involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NWT6].
HIF1AN
hypoxia inducible factor 1 alpha subunit inhibitor
Hypoxia-inducible factor 1-alpha inhibitor
:  DKFZp762F1811 factor inhibiting HIF1 factor inhibiting HIF-1 FIH1 FIH-1 FLJ20615 FLJ22027 hypoxia inducible factor 1, alpha subunit inhibitor hypoxia-inducible factor asparagine hydroxylase Peptide-aspartate beta-dioxygenase
Product
Specifications
Ordering Information
Human
IP, IHC
Between 300 and 349
$339
$99