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FAS Antibody

Tumor necrosis factor receptor superfamily member 6, FAS, functions as the receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated FAS receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) which mediate apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both [taken from the Universal Protein Resource (UniProt) P25445].
Fas cell surface death receptor
Tumor necrosis factor receptor superfamily member 6
:  ALPS1A APO-1 Apo-1 antigen APO-1 cell surface antigen apoptosis antigen 1 apoptosis-mediating surface antigen FAS APT1 CD antigen CD95 CD95 CD95 antigen Fas (TNF receptor superfamily, member 6) Fas AMA FAS1 FASLG receptor FASTM TNF receptor superfamily member 6 TNFRSF6 tumor necrosis factor receptor superfamily, member 6 More... Less...
Ordering Information
Between 285 and 335