FANCM (Fanconi anemia, complementation group M) is a protein involved in DNA repair. Defects in FANCM are the cause of Fanconi anemia, a heterogenous autosomal recessive disorder characterized by congenital malformations and a predisposition to cancer. The FANCM gene is one of 13 complementation groups that include FANCA, FANCB, FANCC, FANCD1/BRCA2, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ/BRIP1, FANCL, FANCM, and FANCN/PALB2. The FANC members are not homologous proteins but are related by their assembly into a common nuclear complex.
ATP-dependent RNA helicase FANCM•
Fanconi anemia complementation group M•
Fanconi anemia group M protein•
fanconi anemia-associated polypeptide of 250 kDa•
protein Hef ortholog•