EXOSC10 Antibody

Exosome component 10 (EXOSC10) is a putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRN. It is also involved in the elimination of RNA-processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q01780].
EXOSC10
exosome component 10
Exosome component 10
:  Autoantigen PM/Scl 2 autoantigen PM-SCL P100 polymyositis-scleroderma overlap syndrome-associated autoantigen p2 p3 p4 PM/Scl-100 PMSCL PM-Scl PMSCL2 polymyositis/scleroderma autoantigen 100 kDa polymyositis/scleroderma autoantigen 2 polymyositis/scleroderma autoantigen 2 (100kD) polymyositis/scleroderma autoantigen 2, 100kDa RRP6 Rrp6p More... Less...
Product
Specifications
Ordering Information
Human, Mouse
WB, IP, IHC
Between 200 to 250
$339
$229
$99
Human
WB, IP, IHC
Between 750 to 800
$339
$229
$99
Human
WB
Between 835 to 885
$339
$229
$99
Human, Mouse
WB, IP, IHC
Includes: 1 each of A303-987A, A303-988A and A303-989A
$707
Includes: 1 each of A303-987A, A303-988A and A303-989A