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Dab2 Antibody

Disabled homolog 2 (Dab2) is an adapter protein that functions as a clathrin-associated sorting protein (CLASP) required for clathrin-mediated endocytosis of selected cargo proteins. Dab2 can bind and assemble clathrin, and binds simultaneously to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and cargos containing non-phosphorylated NPXY internalization motifs, such as the LDL receptor, to recruit them to clathrin-coated pits [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P98082].
DAB2
DAB2, clathrin adaptor protein
Disabled homolog 2
:  adaptor molecule disabled-2 Dab, mitogen-responsive phosphoprotein, homolog 2 differentially expressed in ovarian carcinoma 2 differentially-expressed protein 2 disabled homolog 2 disabled homolog 2, mitogen-responsive phosphoprotein DOC2 DOC-2
Product
Specifications
Ordering Information
Human
WB, IP
Between 275 and 325
$339
$229
$99