Due to inclement weather, Bethyl will be closed Tuesday, January 16 and re-open Wednesday, January 17th at noon. Orders will not be processed until Bethyl re-opens. This is a developing weather situation and may continue to change. Thank you!
DYNLT1 is a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. DYNLT1 regulates the length of primary cilia which are sensory organelles found on the surface of cells. It interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. DYNLT1 protein also interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation [taken from NCBI Entrez Gene (Gene ID: 6993)].