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DNMT3A Antibody

DNA cytosine methyltransferase 3A2 (DNMT3A) is required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. DNMT3A modifies DNA in a non-processive manner and also methylates non-CpG sites. It may preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. DNMT3A plays a role in paternal and maternal imprinting and is required for methylation of most imprinted loci in germ cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y6K1].
DNMT3A
DNA methyltransferase 3 alpha
DNA (cytosine-5)-methyltransferase 3A
:  DNA (cytosine-5-)-methyltransferase 3 alpha DNA (cytosine-5)-methyltransferase 3A DNA cytosine methyltransferase 3A2 DNA methyltransferase HsaIIIA DNA MTase HsaIIIA Dnmt3a DNMT3A2 M.HsaIIIA TBRS
Product
Specifications
Ordering Information
Human, Mouse
WB, IHC
Between 125 and 175
$339
$229
$99