DGCR8 Antibody

DiGeorge syndrome critical region 8 (DGCR8) is a component of the microprocessor complex that acts as a RNA- and heme-binding protein and is involved in the initial step of microRNA (miRNA) biogenesis. DGCR8 functions as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junctions. It directs RNASEN/DROSHA to cleave 11 bp away from the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8WYQ5].
DGCR8
DGCR8 microprocessor complex subunit
Microprocessor complex subunit DGCR8
:  C22orf12 chromosome 22 open reading frame 12 DGCRK6 DiGeorge syndrome critical region 8 DiGeorge syndrome critical region gene 8 Gy1 pasha
Product
Specifications
Ordering Information
Human
WB, IP, IHC
Between 1 and 50
$339
$229
$99
Human
IP, IHC
Between 400 and 450
$339
$99
Human
WB, IP, IHC
Includes: 1 each of A302-468A and A302-469A
$472
Includes: 1 each of A302-468A and A302-469A
Human
IHC
Between 1 and 50
$360
$99