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Chk1, Phospho Antibody

Chk1 functions as a checkpoint protein kinase that is critical to the regulation of the Cdc25a and Cdc25c phosphatases that promote S and G2/M phase progression, respectively. Chk1 kinase activity inhibits cell cycle progression in the presence of DNA damage by phosphorylating Cdc25a and Cdc25c and causing the degradation of Cdc25a and cytoplasmic sequestration of Cdc25c.
checkpoint kinase 1
Serine/threonine-protein kinase Chk1
:  cell cycle checkpoint kinase checkpoint kinase-1 Checkpoint, S. pombe, homolog of, 1 CHK1 CHK1 (checkpoint, S.pombe) homolog CHK1 checkpoint homolog CHK1 checkpoint homolog (S. pombe) Chk1-S
Ordering Information
Surrounding serine 317