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CSN5 Antibody

CSN5 is one of eight subunits (CSN1 to 8) of the highly conserved COP9 signalsome (CSN) complex originally identified as a regulator of light-mediated development in Arabidopsis. Characterization of CSN from yeast to mammals reveals its function as a modulator of signal transduction pathways involved in a variety of cellular and developmental processes. One of the major functions of the CSN is the regulation of protein degradation via intersection with the ubiquitin-proteasome pathway and regulation of E3-ubiquitin ligases. CSN also possesses kinase activity. CSN5 has been identified as the subunit that functions to remove Nedd8, an ubiquitin-like modifier, from cullin-based E3-ubiquitin ligases. CSN5 also functions as a coactivator of nuclear receptors. COP9 signalsome complex subunit 5, signalsome subunit 5, SGN5, jun activation domain-protein 1, COPS5, JAB1, MOV-34, MGC3149.
COP9 signalosome subunit 5
COP9 signalosome complex subunit 5
:  38 kDa Mov34 homolog COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 5 COP9 constitutive photomorphogenic homolog subunit 5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) CSN5 JAB1 jun activation domain-binding protein 1 MOV-34 SGN5 signalosome subunit 5 testis secretory sperm-binding protein Li 231m More... Less...
Ordering Information
Human, Mouse
Between 175 and 225
Human, Mouse
Between 175 and 225