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CD8 Antibody

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain [taken from NCBI Entrez Gene (Gene ID: 925)].
CD8a molecule
T-cell surface glycoprotein CD8 alpha chain
:  CD antigen CD8a CD8 CD8 antigen, alpha polypeptide (p32) Leu2 Leu2 T-lymphocyte antigen MAL OKT8 T-cell antigen p32 T cell co-receptor T8 T-cell antigen T-cell antigen Leu2 T-cell surface glycoprotein CD8 alpha chain T-lymphocyte differentiation antigen T8/Leu-2
Ordering Information
A 13 amino acid synthetic peptide from the C-terminal cytoplasmic domain of alpha chain of human CD8