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CD68 Antibody

CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins.CD68 is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages [taken from NCBI Entrez Gene (Gene ID: 968)].
CD68 molecule
:  CD antigen CD68 CD68 antigen DKFZp686M18236 GP110 LAMP4 macrophage antigen CD68 macrosialin SCARD1 scavenger receptor class D, member 1
Ordering Information
Lysosomal fraction of human lung macrophages