CD146 Antibody

CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. CD146 could be an adhesion molecule active in neural crest cells during embryonic development. CD146 acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P43121].
MCAM
melanoma cell adhesion molecule
Cell surface glycoprotein MUC18
:  CD antigen CD146 CD146 cell surface glycoprotein P1H12 Gicerin melanoma adhesion molecule Melanoma cell adhesion molecule melanoma-associated antigen A32 melanoma-associated antigen MUC18 MUC18 S-endo 1 endothelial-associated antigen
Product
Specifications
Ordering Information
Human, Mouse
WB, IP
Between 600 to 650
$339
$229
$99
Human, Mouse
WB, IP
Between 596 to 646
$339
$229
$99
Human, Mouse
WB, IP
Includes: 1 each of A304-335A and A304-336A
$472
Includes: 1 each of A304-335A and A304-336A