Due to inclement weather, Bethyl will be closed Tuesday, January 16 and re-open Wednesday, January 17th at noon. Orders will not be processed until Bethyl re-opens. This is a developing weather situation and may continue to change. Thank you!
Axl is a receptor tyrosine kinase (RTK) that binds the ligand Gas6 (growth-arrest specific gene). It is part of a sub-family of RTKs that includes Axl, SKY and MER. The Axl gene was first identified as a transforming cDNA isolated from patients with chronic myelogenous leukemia. Axl-Gas6 signaling is implicated in cellular responses such as cell survival, proliferation, migration, and adhesion, and it may be involved in cancer progression.