ATG16 autophagy related 16-like (ATG16L1) is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in the ATG16L1 gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10) [taken from NCBI Entrez Gene (Gene ID: 55054)].
