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ASXL2 Antibody

The gene that encodes Additional sex combs-like protein 2 (ASXL2) is a homolog of the drosophila additional sex combs (Asx) gene. Drosophila Asx is in a class of proteins known as ETP (enhancers of trithorax and polycomb). ETP proteins regulate polycomb-group (PcG) and trithorax-group (trxG) proteins which function to modify the methylation of histones and structure of chromatin. Mutations in ASXL1 are implicated in the development of myelodysplastic syndromes (MDS), a group of hematological diseases characterized by ineffective hematopoiesis and a predisposition to acute myeloid leukemia (AML).
additional sex combs like 2, transcriptional regulator
Putative Polycomb group protein ASXL2
:  additional sex combs like 2 additional sex combs like 2 (Drosophila) additional sex combs like transcriptional regulator 2 additional sex combs-like protein 2 ASXH2 FLJ10898 KIAA1685 polycomb group protein ASXH2
Ordering Information
Between 600 and 650