AF6 Antibody

AF6 was identified as part of a fusion with MLL (mixed lineage leukemia) in a t(6;11) genetic translocation. AF6 is also known as afadin (a splicing variant of AF6 found at adherins junction). AF6/afadin is an actin filament binding protein that binds to nectin at cadherin-based cell-cell adherens junctions and regulates cell-cell adhesion by mediating Ras signaling.
AFDN
afadin, adherens junction formation factor
Afadin
:  adherens junction formation factor AF6 afadin ALL1-fused gene from chromosome 6 protein l-afadin MLL-AF6 MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4 protein AF-6 More... Less...
Product
Specifications
Ordering Information
Human, Mouse
WB, IP
Between 1475 and 1525
$339
$229
$99
Human
WB
Between 1774 and 1824
$339
$229
$99
Human
WB, IP
Includes: 1 each of A302-199A and A302-200A
$472
Includes: 1 each of A302-199A and A302-200A