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ACL Antibody

ATP citrate lyase (ACL) is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. ACL is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ACL may be involved in the biosynthesis of acetylcholine [taken from NCBI Entrez Gene (Gene ID: 47)].
47
ACLY
ATP citrate lyase
ATP-citrate synthase
:  ACL ATP citrate synthase ATP-citrate ATP-citrate (pro-S-)-lyase ATPCL citrate cleavage enzyme CLATP pro-S--lyase
Product
Specifications
Ordering Information
Human, Mouse
WB, IP
Between 350 and 400
$339
$229
$99
Human
WB
Between 1051 and 1101
$339
$229
$99
Human, Mouse
WB, IP
Includes: 1 each of A303-866A and A303-867A
$472
Includes: 1 each of A303-866A and A303-867A