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hIgG4 Antibody

IgG4 represents only 2-5% of the human IgG subclasses in serum. IgG4 lacks effector functions, such as antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity. IgG4 plays a protective role in allergy by acting as a blocking antibody, and inhibiting mast cell degranulation, but a deleterious role in malignant melanoma, by impeding IgG1-mediated anti-tumor immunity.
IGHG4
immunoglobulin heavy constant gamma 4 (G4m marker)
hIgG4
Product
Specifications
Ordering Information
Human
WB, IHC
between 75 and 125
$371
$99