YTHDF1 specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation.
dermatomyositis associated with cancer putative autoantigen 1•
YTH domain family 1•
YTH domain family protein 1•
YTH domain family, member 1•
YTH domain-containing family protein 1•
YTH N(6)-methyladenosine RNA binding protein 1•