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TWIST1 Antibody

TWIST1 is a basic helix-loop-helix (bHLH) transcription factor that plays an important role in embryonic development. TWIST1 forms both homodimers and heterodimers that bind to DNA E box sequences and regulate the transcription of genes involved in cranial suture closure during skull development. TWIST1 may also regulate neural tube closure, limb development and brown fat metabolism. The TWIST1 gene is hypermethylated and overexpressed in multiple human cancers, and the encoded protein promotes tumor cell invasion and metastasis, as well as metastatic recurrence. [taken from NCBI Entrez Gene (Gene ID: 7291)].
twist family bHLH transcription factor 1
Twist-related protein 1
:  ACS3 B-HLH DNA binding protein bHLHa38 BPES2 BPES3 class A basic helix-loop-helix protein 38 CRS CRS1 CSO H-twist SCS SWCOS TWIST twist basic helix-loop-helix transcription factor 1 twist homolog 1 TWIST homolog of drosophila twist-related protein 1
Ordering Information
between 1 and 50