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RUNX3 Antibody

RUNX3 is a member of the runt domain-containing family of transcription factors. A heterodimer of RUNX3 and CBFB forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters. This complex binding can either activate or suppress transcription to control cellular proliferation and/or differentiation, in particular cytotoxic T cell differentiation. [taken from the Universal Protein Resource (UniProt)].
runt related transcription factor 3
Runt-related transcription factor 3
:  acute myeloid leukemia 2 protein acute myeloid leukemia gene 2 AML2 CBFA3 CBF-alpha-3 core-binding factor subunit alpha-3 core-binding factor, runt domain, alpha subunit 3 oncogene AML-2 PEA2 alpha C PEA2-alpha C PEBP2 alpha C PEBP2aC PEBP2-alpha C polyomavirus enhancer-binding protein 2 alpha C subunit runt-related transcription factor 3 SL3/AKV core-binding factor alpha C subunit SL3-3 enhancer factor 1 alpha C subunit transcription factor AML2 More... Less...
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