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LZTFL1 Antibody

LZTFL1 is a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in its gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This protein may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. [provided by RefSeq, Feb 2013] [taken from NCBI Entrez Gene (Gene ID: 54585)].
leucine zipper transcription factor like 1
Leucine zipper transcription factor-like protein 1
:  BBS17 leucine zipper transcription factor-like protein 1
Ordering Information
Human, Mouse
between 150 and 200
between 249 and 299