LAT Antibody

LAT is required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O43561].
LAT
linker for activation of T cells
Linker for activation of T-cells family member 1
:  36 kDa phospho-tyrosine adapter protein 36 kDa phospho-tyrosine adaptor protein IMD52 LAT1 linker for activation of T cells, transmembrane adaptor linker for activation of T-cells family member 1 p36-38 pp36
Product
Specifications
Ordering Information
Human
WB, IP
between 212 and 262
$229
$99