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IDO1 Antibody

Indoleamine 2,3-dioxygenase (IDO1) is a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. IDO1 acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. It is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan [taken from NCBI Entrez Gene (Gene ID: 3620)].
indoleamine 2,3-dioxygenase 1
Indoleamine 2,3-dioxygenase 1
:  IDO IDO-1 INDO indolamine 2,3 dioxygenase indole 2,3-dioxygenase indoleamine-pyrrole 2,3 dioxygenase indoleamine-pyrrole 2,3-dioxygenase
Ordering Information
recombinant protein representing Human IDO1