HVEM/TNFRSF14 is a member of the tumor necrosis factor receptor superfamily. It functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. HVEM/ TNFRSF14 also binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. [taken from NCBI Entrez Gene (Gene ID: 8764)].